- Abington, The Chaiken Center for Student Success
- Altoona, Robert B. Smith Learning Resources Center
- Beaver, Center for Academic Achievement
- Behrend, Learning Resource Center
- Berks
- Brandywine
- DuBois, Center for Undergraduate Excellence (CUE)
- Fayette, The Eberly Campus, Student Success Center
- Hazleton, Student Success Center
- Harrisburg, Russell E. Horn Sr. Learning Center
- Lehigh Valley, The Learning Center
- Greater Allegheny, John H. Gruskin Learning Center
- Mont Alto, Academic Support Center
- New Kensington, Learning Center
- Schuylkill, Academic Resource Center
- Scranton, The Learning Center
- Shenango, Shenango Academic Resource Center (SHARC)
- University Park, Penn State Learning
- Wilkes-Barre, The Learning Center
- World Campus, Academic Support Center
- York, Nittany Success Center
